BDBM50221416 22-methyl-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaene-2,16-diol(HCl0.5H2O) (Oxymorphindole, OMI)::22-methyl-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaene-2,16-diol::CHEMBL401093::OXYMORPHINDOLE
SMILES CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@]3(O)Cc1c4[nH]c2ccccc12)ccc5O
InChI Key InChIKey=YQNZUKAKYJMEFE-LMDOGRNLSA-N
Data 17 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50221416
Affinity DataKi: 515nMAssay Description:Displacement of [3H]U-69593 from cloned kappa opioid receptorMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Universit£T Des Saarlandes
Curated by ChEMBL
Universit£T Des Saarlandes
Curated by ChEMBL
Affinity DataKi: 2.17E+3nMAssay Description:Binding affinity to kappa opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 4.47E+3nMAssay Description:Binding affinity was measured by the displacement of [3H]- EK in guinea pig brain membrane of opioid receptor kappaMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 4.47E+3nMAssay Description:The compound was evaluated for binding affinity against the opioid receptor kappa in guinea pig brain membranes using [3H]- U-69,593More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 4.47E+3nMAssay Description:Binding affinity was measured by the displacement of [3H]- EK in guinea pig brain membrane of opioid receptor kappaMore data for this Ligand-Target Pair